Pyruvate kinase M2 contributes to TLR-mediated inflammation and autoimmunity by promoting Pyk2 activation
We found that PA-S14 promotes mitochondrial biogenesis via LKB1-AMPK-PGC-1 signaling pathway, which protects against renal TECs cell senescence, renal fibrosis in various CKD models, such as unilateral ureteral obstruction (UUO), unilateral ischemia-reperfusion injury (UIRI), adriamycin nephropathy and 5/6 nephrectomized model (Table 1)
[DOI] [PMC free article] [PubMed] [Google Scholar] 102.Li L, Li S, Deng K, Liu J, Vandvik PO, Zhao P, et al
Gorbatenko VO, Goriainov SV, Babenko VA et al (2022) Anti-inflammatory properties of metformin during cultivation of primary rat astrocytes in a medium with high glucose concentration
Bottled drinking water offers no guarantee of sterility or appropriate mineral content